Based　on　one　dimensional　large-strain　consolidation　equations,　the　expressions　of　large-strain　coefficient　of　consolidation　in　different　coordinates　and　variables　are　given　in　this　paper.　In　order　to　study　the　variation　regularity　of　large-strain　coefficient　of　consolidation　with　void　ratio,　it　is　introduced　that　the　coefficient　of　permeability-void　ratio　and　effective　stress-void　ratio　follow　the　semilogarithm　linear　and　power　function　relation　for　soft　clay　soil.　The　condition　relationship　formulae　of　variation　of　large-strain　coefficient　of　consolidation　with　void　ratio　is　proposed,　which　is　applied　to　the　analysis　on　coefficient　of　consolidation　of　dredged　fill　in　GDS　consolidation　and　permeability　tests.　The　obtained　results　verifies　that:　1)　Three　kinds　of　large-strain　coefficient　of　consolidation　are　divided　into　different　monotony　intervals　by　the　critical　void　ratio.　The　condition　relationship　formulae　can　be　applied　preferably　in　determining　the　variation　regularity　of　large-strain　coefficient　of　consolidation.　2)　the　large-strain　coefficient　of　consolidation　of　dredged　fill　varied　1-2　orders　of　magnitude　with　the　decrease　of　the　void　ratio　in　Shenzhen　Qianwan　area,　of　which　the　variation　is　more　larger　than　small-strain　coefficient　of　consolidation.　The　variation　regularity　of　large-strain　coefficient　of　consolidation　should　be　understood　before　large-strain　consolidation　calculation　of　dredged　fill　is　conducted.