Protein IsoformsCell DivisionChromosomeSegregationDNA RepairProtein BindingModels, MolecularIn eukaryotes, the process of sister chromatid cohesion hol...
The centromere is the region of the chromosome that directs its segregationinmitosis and meiosis. Although the functional importance of the centromere...
During cell division, interaction between kinetochores and dynamic spindle microtubules governs chromosome movements. The microtubule depolymerase mitot...
Background: Hec1 is a core component of outer kinetochore essential for chromosomesegregationinmitosis. Results: Hec1 interactswith mitotic checkpoi...
Mitosis is an orchestration of dynamic interaction between chromosomes and spindle microtubules by which genomic materials are equally distributed into ...
Topoisomerases are essential for chromosome metabolism. Tang etal. show that the Top3-Rmi1 complex must decatenate DNA strands to process intermediates during homologous recombination. Top3-Rmi1 partners with BLM/Sgs1 to prevent abnor...