Research　has　shown　that　thrombus,　stenosis,　aneurysm,　atherosclerosis　and　other　vascular　diseases　are　likely　to　occur　in　curved　arteries　such　as　aortic　arch,　coronary　artery　and　cerebral　artery.　It　is　found　that　fatigue　damage　and　failure　of　arteries　are　closely　associated　with　the　dynamic　physiological　environment　where　the　arteries　are　situated.　Based　on　these　considerations,　the　behaviour　of　curved　arteries　subjected　to　a　physiological　environment　is　presented　in　this　paper.　The　fluidstructure　interaction　(FSI)　effect　is　considered.　Wall　stress　distribution　and　its　variation　over　time　are　investigated.　Artery　deformation　regularity　throughout　the　cardiac　cycle　has　been　analysed.　It　is　believed　that　this　study　may　provide　insights　into　clinical　research　in　the　future.　©　2011　Informa　UK,　Ltd.