Graphene　quantum　dots　(GQDs)　were　connected　to　[Ru(bpy)(3)](2+)　to　sense　DNA-mediated　charge　transfer.　Interaction　between　abasic　site　double　stranded　DNA　(Abasic-DNA)　and　[Ru(bpy)(3)-GQD](2+)　was　investigated　by　absorption　spectroscopy,　gel　electrophoresis,　circular　dichroism,　and　melting　temperature　measurements.　The　results　indicate　that　[Ru(bpy)(3)-GQD](2+)　could　be　intercalated　into　double　stranded　DNA.　Using　[Ru(bpy)(3)-GQD](2+)　as　a　signal　molecule,　the　charge　transfer　performance　of　DNA-intercalated　[Ru(bpy)(3)-GQD](2+)　was　determined　using　electrochemical　and　electrochemiluminescence　measurements.　Various　DNA　types　were　immobilized　on　Au　electrodes　via　Au-S　bonds.　Electrochemiluminescence　and　electrochemical　measurements　indicate　that　[Ru(bpy)(3)-GQD](2+)　could　enhance　DNA-mediated　charge　transfer　when　intercalated　into　an　abasic　site　of　double　stranded　DNA.　And　comparing　with　[Ru(bpy)(3)](2+),　it　can　be　concluded　that　GQDs　intercalate　into　the　DNA　duplex　by　acting　as　a　base　analog,　thus　enhancing　DNA　charge　transfer.　These　findings　suggest　that　the　DNA-GQD　structure　could　aid　the　development　of　molecular　devices　and　electric　drivers,　and　broaden　the　application　of　DNA　charge　transfer.