The　vertical　vibrations　of　building　structures　under　ambient　vibration　or　earthquake　could　not　be　ignored,　and　vertical　vibration　isolation　devices　are　needed　to　reduce　the　dynamic　amplitude.　The　isolated　structure　model　considering　human-structure　dynamic　interaction　is　more　objective,　and　the　human　responses　can　be　also　obtained.　Disk　spring　bearing　is　introduced　as　vertical　base　isolation　damper,　and　vertical　human　body　models　with　different　postures　are　selected　according　to　ISO5982,　hence　the　dynamic　coupling　equations　with　non-classical　damping　for　base　isolation　structure　and　human　are　established.　The　dynamic　equations　are　decoupled　by　complex　modal　analysis　method.　A　10-story　building　is　studied　to　analyze　the　performance　of　disk　spring　bearings　and　the　human-structure　dynamic　interaction.　The　results　show　that　the　vibration　reduction　effects　of　floors　in　the　structure　with　uniform　mass　and　stiffness　are　more　obvious　when　the　numbers　of　human　occupants　increase.　The　vertical　vibration　on　floors　decrease　remarkably　and　the　human　comfort　is　improved　when　the　disk　spring　bearings　are　installed.