Anaerobic　ammonium　oxidation　(anammox)　has　been　extensively　investigated　for　cost-efficient　nitrogen　removal　from　wastewater.　However,　the　major　issues　of　nitrate　(NO3--N)　residue　and　instability　in　the　current　combination　of　nitritation　and　anammox　process　necessitates　being　addressed　efficiently.　The　recently　proposed　partial-denitrification　(PD),　terminating　NO3--N　reduction　to　nitrite　(NO2--N),　has　been　regarded　as　a　promising　alternative　of　NO3--N　supplying　for　anammox　bacteria.　Given　the　engineering　practices,　the　steadily　high　NO3--N　production,　alleviating　organic　inhibition,　and　reducing　greenhouse　gas　of　PD　process　offers　a　viable　and　efficient　approach　for　anammox　implementation.　Moreover,　it　allows　for　the　extending　applications　of　anammox　process　due　to　the　NO3--N　removal　availability.　Here　we　comprehensively　review　the　important　new　outcomes　and　discuss　the　emerging　applications　of　PD-based　anammox　including　the　process　development,　mechanism　understanding,　and　future　trends.　Significant　greater　stability　and　enhanced　nitrogen　removal　efficiency　have　been　demonstrated　in　the　novel　integrations　of　PD　and　anammox　process,　indicating　a　broad　perspective　in　dealing　with　the　mainstream　municipal　sewage,　ammonia-rich　streams,　and　industrial　NO3--N　contained　wastewater.　Furthermore,　researches　are　still　needed　for　the　predictable　and　controllable　strategies,　along　with　the　detailed　microbiological　information　in　future　study.　Overall,　the　achievement　of　PD　process　provides　unique　opportunity　catalyzing　the　engineering　applications　of　energy-efficient　and　environmental-friendly　wastewater　treatment　via　anammox　technology.