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作者:

Hao, Dongmei (Hao, Dongmei.) | Qin, Wen (Qin, Wen.) | Yu, Chunshui (Yu, Chunshui.) | Dong, Huiqing (Dong, Huiqing.) | Liu, Nan (Liu, Nan.)

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摘要:

To investigate changes of functional activation areas of the cerebral cortex and the connectivity of motor cortex networks (MCNS) in stroke patients during the recovery, five patients with the infarct in their left hemispheres are recruited. Functional magnetic resonance imaging (fMRI) is performed in the second, fourth, eighth, and sixteenth weeks after the stroke. Images are analyzed using the professional software SPM5 to obtain the bilateral activation of the motor cortex in left and right handgrip tests. MCN data are extracted from the active areas, and the structural and functional characteristic parameters are computed to indicate the connectivity of the network. Results show that the ipsilesional hemisphere recruits more areas with less active extent during the handgrip test, compared with the contralesional hemisphere. MCN shows a higher overall degree of statistical independence and more statistical dependence among motor areas with the gradual recovery. It can help physicians understand the recovery mechanism.

关键词:

Brain Chemical activation Computer system recovery Functional neuroimaging Magnetic resonance imaging Patient rehabilitation Recovery Software testing

作者机构:

  • [ 1 ] [Hao, Dongmei]College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China
  • [ 2 ] [Qin, Wen]Xuan Wu Hospital, Capital Medical University, Beijing 100053, China
  • [ 3 ] [Yu, Chunshui]Xuan Wu Hospital, Capital Medical University, Beijing 100053, China
  • [ 4 ] [Dong, Huiqing]Xuan Wu Hospital, Capital Medical University, Beijing 100053, China
  • [ 5 ] [Liu, Nan]Xuan Wu Hospital, Capital Medical University, Beijing 100053, China

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来源 :

Transactions of Nanjing University of Aeronautics and Astronautics

ISSN: 1005-1120

年份: 2010

期: 1

卷: 27

页码: 55-61

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