The　preozonation　and　carbon　nanotubes　(CNTs)　modification　of　hollow　fiber　membranes　for　fouling　control　was　systematically　evaluated　when　treating　real　sewage　effluent.　The　hybrid　process　was　operated　in　cyclical　flow　filtration　system,　involving　filtrating　and　backwashing　processes.　The　results　revealed　that　preozonation　and　CNTs　modification　improved　fouling　control　and　permeate　quality.　After　preozonation,　the　fouling　rate　of　the　CNTs　modified　membrane　was　reduced　and　its　recoverability　was　effectively　improved.　With　increased　ozone　dosage,　the　hybrid　effectiveness　of　preozonation　and　CNTs　modification　on　fouling　control　was　enhanced.　The　recoverability　of　CNTs　modified　membranes　in　the　hybrid　process　was　improved　by　increasing　the　frequency　of　backwashing.　Compared　with　CNTs＇　adsorption　effect,　the　interception　effect　of　CNTs　layer　pre-deposited　during　membrane　modification　increased　permeate　quality　and　reduced　membrane　fouling.　The　interception　effect　of　CNTs　layer　was　enhanced　after　preozonation.　Confocal　laser　scanning　microscope　results　demonstrated　that　the　hybrid　preozonation　and　CNTs　modification　membrane　process　effectively　controlled　biofouling.　After　preozonation,　the　presence　of　CNT　layers　on　membrane　surfaces　could　further　decrease　the　amount　of　living　bacteria.　The　attachment　of　dead　bacteria　to　CNTs　modified　membrane　was　also　decreased　after　preozonation.