Dynamic　observation　of　dissolving-crystallization　process　of　NaCl　crystal　and　in-situ　reaction　of　BiVO4　crystal　were　carried　out　by　using　an　environmental　scanning　electron　microscope　(ESEM)　and　the　micro-manipulator/micro-injector　system　(MMI/MIS).　The　step　precision　of　MMI　system　in　three　directions,　retreat-forward　linearity　(Z-axis),　clock-unclockwise　rotation　(X-axis)　and　up-down　rotation　(Y-axis)　are　5,　5　and　0.5　nm,　respectively.　The　size　of　the　liquid　droplet　of　MIS　system　was　about　200m-300m.　The　influences　of　the　water　wetting　environment　on　dissolving,　growth　and　growing　rate　of　crystals　were　studied　by　changing　pressures　(450-850　Pa)　in　chamber　and　sample　temperatures　(0-50C),　as　well　as　by　controlling　states　of　water　evaporation　and　condensation.　Reactive　products　of　BiVO4!　octahedron　were　obtained　at　700　Pa　and　4C　via　liquid　micro-injection　approach　by　using　two　MMI/MIS　systems,　i.e.,　one　for　NH4VO3　and　one　for　Bi(NO3)3　injection.