• 综合
  • 标题
  • 关键词
  • 摘要
  • 学者
  • 期刊-刊名
  • 期刊-ISSN
  • 会议名称
搜索

作者:

Gao, Xiang (Gao, Xiang.) | Tian, Zhen (Tian, Zhen.) | Cheng, Yanyan (Cheng, Yanyan.) | Geng, Binghao (Geng, Binghao.) | Chen, Shilin (Chen, Shilin.) | Nan, Qun (Nan, Qun.)

收录:

EI Scopus SCIE PubMed

摘要:

Microwave ablation is used to treat lung tumors by releasing microwave magnetic field to produce high temperature of more than 60 celcius in the tumor tissues, thus causing tissue coagulation, dehydration and necrosis to achieve the purpose of treatment. However, the lack of appropriate power and time parameters for microwave ablation in clinical treatment of lung tumors leads to poor ablation or excessive ablation. In this paper, a two-dimensional simulation model of microwave antenna and ideal lung was established to realize the simulation of microwave ablation process. Meanwhile, microwave ablation experiments were carried out in ex-vivo porcine lung under different power and time. The temperature distribution was obtained by thermocouples and compared with the simulation calculation. Set 60celcius as boundary of the ablation area and the ablation time was 360 s. The length of the ablation area parallel to the antenna direction is longitudinal, and the length perpendicular to the antenna direction is transverse. From the simulation results, with the increase of ablation power (20 W to 60 W), the transverse diameter of ablation area increased from 32.5 mm to 55.6 mm, and the longitudinal diameter increased from 47.8 mm to 69.1 mm. From the results of ex-vivo experiments, with the increase of ablation power (30 W to 50 W), the transverse diameter of ablation area increased from 29.5 mm to 48.9 mm, the longitudinal diameter increased from 41.1 mm to 66.3 mm, and the maximum slot temperature increased from 75.6 celcius to 106.7 celcius. The results of numerical simulation are slightly larger than those of ex-vivo experiments under the same parameters. When the average diameter of lung tumors is less than 40 mm, 30 W and 40 W ablation power can be selected. The ablation time is limited to 360 s. 50 W ablation power can be used to ablate the lesion quickly in a shorter time to achieve the same purpose. Although there are differences between ex-vivo and in vivo, the validity of the lung model and the influence of ablation parameters in the simulation are verified in this paper. The ablation area under different parameters was obtained, which served as a reference data for clinical practice. A basic study was made to consider the complex lung model and the changes of parameters with temperature in the future.

关键词:

ex-vivo experiment lung Microwave ablation numerical simulation temperature field

作者机构:

  • [ 1 ] [Gao, Xiang]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 2 ] [Tian, Zhen]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 3 ] [Cheng, Yanyan]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 4 ] [Geng, Binghao]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 5 ] [Nan, Qun]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 6 ] [Chen, Shilin]Jiangsu Caneer Hosp, Nanjing, Jiangsu, Peoples R China

通讯作者信息:

  • [Nan, Qun]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China

电子邮件地址:

查看成果更多字段

相关关键词:

相关文章:

来源 :

ELECTROMAGNETIC BIOLOGY AND MEDICINE

ISSN: 1536-8378

年份: 2019

期: 4

卷: 38

页码: 249-261

1 . 7 0 0

JCR@2022

ESI学科: BIOLOGY & BIOCHEMISTRY;

ESI高被引阀值:61

JCR分区:3

被引次数:

WoS核心集被引频次: 14

SCOPUS被引频次: 9

ESI高被引论文在榜: 0 展开所有

万方被引频次:

中文被引频次:

近30日浏览量: 1

在线人数/总访问数:1364/2907664
地址:北京工业大学图书馆(北京市朝阳区平乐园100号 邮编:100124) 联系我们:010-67392185
版权所有:北京工业大学图书馆 站点建设与维护:北京爱琴海乐之技术有限公司