In　this　paper,　wind　pressure　coefficients　of　pitched　roofs　in　different　horizontal　wind　directions　are　firstly　computed　by　computational　fluid　dynamics　(CFD)　software,　and　then　wind　pressure　coefficients　of　membrane　structures　considering　fluid　structure　interaction　(FSI)　are　computed.　The　results　of　pitched　roofs　are　compared　with　those　of　wind　tunnel　experiments,　and　it　shows　that　CFD　software　can　predict　wind　pressure　coefficients　of　pitched　roofs.　In　addition,　the　result　indicates　that　FSI　has　more　influence　on　the　distribution　and　magnitude　of　wind　pressure　coefficients;　and　the　prestress　can　affect　wind　pressure　coefficients　of　membrane;　moreover　the　deformation　pattern　of　membrane　changes　when　wind　velocity　increases.