The　bone　remodelling　is　a　refresh　and　readjust　process　of　bone　structure.　In　this　paper,　a　new　method　for　topology　optimization　of　continuum　structure　based　on　ICM　(independent　continuous　mapping)　method　is　taking　advantage　in　bone　remodelling　field.　The　continuum　structure　is　optimized　as　a　piece　of　bone　which　obeys　Wolff＇s　law,　a　globalization　of　stress　constraints　is　proposed　by　virtue　of　the　von　Mises＇　yield　criterion　in　machanics　of　materials.　Thus,　transformation　of　the　local　stress　constraints　of　element　into　the　global　stain　energy　constraints　of　structure　is　achieved.　The　dual　quadratic　programming　is　applied　for　to　solve　the　optimal　model　of　continuum.　Numerical　examples　indicate　that　the　method　is　effective　and　efficient.