It　is　necessary　to　study　structural　vibration　induced　by　human　walking　and　human　comfort　for　important　flexible　beam-slab　structures.　A　time-varying　dynamic　human　model　including　a　main　part　and　coupled　masses　is　established　according　to　different　footfall　force　curves.　The　dynamic　coupled　equations　for　a　beam-slab　structure　and　a　walking　human　are　also　established　and　their　analytical　expressions　are　given.　Considering　the　human　walking　velocity　and　the　slab　length,　the　dynamic　responses　of　the　structure　and　the　human　are　studied　and　compared.　The　results　indicate　that　the　human　natural　frequency,　walking　frequency　and　velocity　are　the　most　important　factors　to　influence　the　structural　responses　and　the　human　comfort.　These　factors　should　be　considered　during　design　in　order　to　reduce　the　structural　vibration　amplitude.　Compared　with　the　equivalent　static　method　and　the　dynamic　method　without　inferactions　between　human　and　structure,　the　dynamic　coupled　method　is　more　comprehensive　and　correct.