Copper　selenide　(Cu2Se)　has　been　extensively　studied　as　an　eco-friendly　thermoelectric　candidate　owing　to　the　outstanding　thermoelectric　performance　of　its　high-temperature　beta-phase.　In　this　study,　we　propose　that　alpha-Cu2Se　is　also　a　promising　thermoelectric　material　at　near-room-temperature.　We　synthesize　nanostructured　Cu2-xSe　via　a　facile　solvothermal　method,　and　densify　the　samples　using　Spark　Plasma　Sintering　to　maintain　the　small　grain　sizes.　Although　the　as-prepared　alpha-Cu2Se　has　intrinsically　low　lattice　thermal　conductivity,　its　high　Cu　deficiency　leads　to　a　high　carrier　concentration,　therefore,　a　low　thermoelectric　performance.　As　an　electron　donor,　bismuth　can　effectively　compress　the　Cu　vacancies　of　the　as-prepared　alpha-Cu2Se　and　in　turn　reduce　its　carrier　concentration　from　4.1　x　10(20)　to　2.0　x　10(20)　cm(-3)　at　room　temperature,　achieving　a　significantly　enhanced　power　factor　and　a　reduced　carrier　thermal　conductivity.　Consequently,　a　zT　of　0.43　at　373　K　is　obtained　in　Cu1.982Bi0.006Se,　showing　great　potential　in　developing　high-performance　near-room-temperature　alpha-Cu2Se-based　thermoelectric　materials.