To　consider　the　effects　of　the　dynamics　of　flexible　manipulators　and　control　strategy　synthetically　and　improve　the　system　integral　performance　further,　the　integrated　system　optimization　mathematical　model　is　established　which　includes　construction　parameters,　sensor　parameters,　controller　parameters　and　driver　parameters　based　on　the　concurrent　design.　An　improved　genetic　algorithms　is　used　for　parameters　global　optimization　under　the　integration　optimization　object.　Design　results　are　that　the　optimized　manipulator　beam　is　non-uniform　cross-section　beam　and　the　controller　is　not　only　easy　to　implement　but　also　robust　to　the　system　parameters　uncertainty.　The　research　demonstrates　that　the　global　optimization　design　improves　the　system　integrated　performances　and　has　better　tip　vibration　suppression　result　without　increasing　the　system　energy　cost　based　on　the　concurrent　design　idea.