An apparatus for studying the response of cultured endothelial cells to stresses - 文章详情页

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EI Scopus

摘要：

In　order　to　simulate　the　hemodynamic　environment　of　human　arteries　in　vivo,　we　designed　a　laminar　flow　apparatus　which　can　precisely　simulate　the　normal　stress　and　shear　stress　to　which　cultured　endothelial　cells　are　exposed.　Under　both　normal　and　abnormal　physiological　conditions,　this　apparatus　can　accurately　control　and　adjust　the　values　of　normal　stress　and　shear　stress　and　the　frequency　of　pulse　waves,　as　well　as　the　amplitude　of　pulsatile　flow.　This　in　vitro　apparatus　provides　an　experimental　platform　for　studying　the　response　of　the　biological　characteristics　of　cultured　endothelial　cells　in　a　hemodynamic　environment.　Copyright　©　2006　ACPSEM/EA.

关键词：

Body fluids Cell culture Computer simulation Hemodynamics Physiology Pulsatile flow Shear stress

作者机构：

[ 1 ] [Shen, L.]Biomechanics and Medical Information Institute, Beijing University of Technology, Beijing 100022, China
[ 2 ] [Shen, L.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
[ 3 ] [Qiao, A.]Biomechanics and Medical Information Institute, Beijing University of Technology, Beijing 100022, China
[ 4 ] [Ding, H.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
[ 5 ] [Mo, G.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
[ 6 ] [Xu, G.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
[ 7 ] [Du, Y.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
[ 8 ] [Li, M.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
[ 9 ] [Chen, Z.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
[ 10 ] [Zeng, Y.]Biomechanics and Medical Information Institute, Beijing University of Technology, Beijing 100022, China

通讯作者信息：

[zeng, y.]biomechanics and medical information institute, beijing university of technology, beijing 100022, china

电子邮件地址：

yjzeng@bjut.edu.cn

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