Houston,　Texas,　is　one　of　the　earliest　urban　areas　to　employ　Global　Positioning　System　(GPS)　technology　for　land　subsidence　and　fault　monitoring.　As　of　2020,　the　University　of　Houston　and　the　Harris-Galveston　Subsidence　District　have　integrated　over　230　permanent　GPS　stations　into　their　routine　GPS　data　processing　for　regional　subsidence　and　fault　monitoring.　This　article　summarizes　the　GPS　geodetic　infrastructure　in　the　Greater　Houston　region.　The　infrastructure　is　comprised　of　two　components:　a　dense　GPS　network　(HoustonNet)　and　a　stable　regional　reference　frame　(Houston20).　Houston20　is　realized　by　25　long-history　(　＞　8　years)　continuous　GPS　stations　located　outside　the　subsiding　area　and　is　aligned　in　origin　and　scale　with　the　International　GNSS　Reference　Frame　2014　(IGS14).　The　stability　of　the　regional　reference　frame　is　below　1mmyr-1　in　all　three　directions.　GPS-derived　ground　deformation　rates　(2010-2019)　within　the　Greater　Houston　region　are　also　presented　in　this　article.　©　Author(s)　2020.