In　order　to　improve　the　separation　performance　of　the　nanofiltration　(NF)　membranes,　numerous　inorganic　components　have　been　introduced　into　polymer　membranes.　Molybdenum　disulfide　(MoS2)　is　an　emerging　graphene-like　nanomaterials,　which　has　many　advantages,　and　expected　to　have　novel　applications　in　the　NF　fields.　Herein,　this　work　the　PDDA　modified　MoS2　nanosheets　were　prepared,　which　showed　better　dispersion　in　aqueous　solution,　and　the　modified　PDDA@MoS2　displayed　higher　compatibility　with　the　polyelectrolyte.　Then,　the　prepared　PDDA@MoS2　nanosheets　was　introduced　into　polyelectrolyte　membrane　through　LbL　self-assembled　method　to　get　an　organic/inorganic　composite　NF　membrane　with　ceramic　tube　as　substrate.　The　membrane　was　used　to　NF　separation　of　dyes　from　aqueous　solution.　The　results　suggested　that　the　membrane　flux　increased　first　and　then　decreased　with　increasing　PDDA@MoS2　nanosheets　concentration,　while　the　rejection　remained　almost　constant.　Specifically,　under　optimum　condition,　the　prepared　(PSS/PDDA-MoS2)　4.5　ceramic　composite　membrane　showed　97.2%　of　rejection　for　0.20　g/L　methyl　blue　dye　solution,　along　with　flux　of　163.2　L.m(-2).h(-1).MPa-1,　which　was　similar　to　2.4　times　compared　with　pure　(PSS/PDDA)　4.5　membrane　without　sacrificing　rejection.