Herein　we　fabricated　the　supported　single-atom　silver　catalysts　using　an　in　situ　molten　salt　method.　The　Mn2O3　nanowires　supported　single-atom　silver　catalyst　(i.e.,　0.06　wt%　Ag/Mn2O3)　exhibited　excellent　catalytic　activity　for　toluene　combustion,　with　the　temperatures　required　for　50　and　90%　of　toluene　conversions　being　170　and　205　degrees　C,　respectively,　at　a　space　velocity　of　40,000　mL/(g　h).　However,　the　toluene　conversion　at　205　degrees　C　quickly　decreased　from　90　to　30%　within　2.5　h　of　on-stream　reaction.　Based　on　the　various　characterization　results,　we　found　that　there　were　no　aggregation　of　Ag　particles,　no　change　in　crystal　structure　of　the　Mn2O3　nanowire　support,　and　no　carbon　deposition　on　the　catalyst　surface,　and　the　quick　deactivation　of　0.06　wt%　Ag/Mn2O3　was　mainly　associated　with　the　low　oxygen　activation　ability.　The　proper　CeO2　addition　to　the　0.06　wt%　Ag/Mn2O3　catalyst　was　found　to　not　only　improve　the　catalytic　activity　but　also　significantly　enhance　the　stability　of　the　catalyst.　Toluene　conversion　at　195　degrees　C　over　0.63　wt%　CeO2-0.06　wt%　Ag/Mn2O3　decreased　by　only　10%　in　50　h　of　on-stream　reaction.　Because　Ag　and　CeO2　particles　were　highly　dispersed　on　the　Mn2O3　nanowire　support,　the　oxygen　species　formed　at　the　surface　oxygen　vacancies　of　CeO2　could　efficiently　migrate　to　the　active　sites　(i.e.,　the　interface　of　Ag-Mn2O3)　and　replenish　the　surface　reactive　lattice　oxygen　species.　Thus,　the　present　single-atom　silver　catalyst　is　an　alternative　for　commercial　noble　metal　catalysts　for　the　removal　of　VOCs.