The　limestone-gypsum　wet　flue　gas　desulfurization　system　has　been　widely　used　due　to　its　remarkable　desulfurization　effect,　but　there　are　still　problems　such　as　high　operation　and　maintenance　costs,　difficult　control　of　process　indicators,　and　large　energy　consumption.　In　view　of　the　above　problems,　this　paper　proposes　to　apply　the　Cyber-Physical　System　(CPS)　to　the　wet　flue　gas　desulfurization　(WFGD)　process,　and　construct　a　architecture　suitable　for　(WFGD)　system　according　to　the　CPS　5C　architecture　and　NIST　CPS　framework,　and　introduce　the　architecture　in　detail　around　the　above　problems.　Applying　the　advanced　technology　of　CPS　to　the　(WFGD)　system　can　improve　the　whole　system　operation　efficiency　and　reduce　energy　waste,　and　has　good　utilization　value　for　promoting　the　intelligent　upgrade　of　the　factory.　©　2019　IEEE.