Carbon　nanotubes　are　recognized　as　an　advanced　anode　material　for　electrocatalysis　oxidation　recalcitrant　antibiotics　in　wastewater.　In　this　study,　a　novel　La2O3　-CuO2　/CNTs　electrode　was　synthesized　by　solvothermal　method　and　calcination　in　nitrogen　atmosphere.　Scanning　electron　microscopy　(SEM),　X-ray　diffraction　(XRD)　and　X-ray　photoelectron　spectroscopy　(XPS)　were　conducted　to　illustrate　the　structure　and　elemental　composition,　and　the　La　and　Cu　bimetallic　composite　oxide　(La2O3　-CuO2)　were　observed　on　the　surface　of　carbon　nanotubes.　Cyclic　voltammetry　analysis　showed　that　the　modified　electrode　had　better　catalytic　activity　and　stable　working　lifetime.　The　Tafel　curves　indicated　that　the　corrosion　potential　of　the　electrode　increased　while　the　corrosion　current　density　decreased.　The　degradation　of　ceftazidime　by　modified　electrode　was　studied　through　optimization　of　five　parameters,　including　current　density,　electrode　space,　electrolyte　concentration,　pH　and　volume　of　solution.　The　results　demonstrated　that　La2O3　-CuO2　/CNTs　electrode　exhibited　the　electrochemical　degradation　efficiency　of　90%　towards　1　mg　L-1　ceftazidime　within　30　min,　which　is　much　higher　than　those　of　pristine　CNTs　and　dimensional　stable　anode.　The　optimal　operating　conditions　were:　volume　of　100　mL,　1　g　L-1　Na-2　SO4　as　electrolyte,　current　density　of　0.8mA-cm(-2)　,　and　electrode　space　is　2　cm.　The　degradation　intermediates　and　routes　of　ceftazidime　under　modified　electrode　were　deduced　by　LC-MS　analysis.　These　results　suggest　that　La2O3　-CuO2/CNTs　electrodes　can　be　considered　as　promising　catalysts　for　treating　bio-refractory　antibiotics　with　relatively　low　concentration.