Single-atom　catalysts　are　a　kind　of　promising　catalytic　materials　that　can　use　the　precious　metal　more　efficiently.　The　KIT-6-templaing　method　was　adopted　to　obtain　three-dimensionally　ordered　mesoporous　iron　oxide　(meso-Fe2O3).　The　meso-Fe2O3-supported　single-atom　Pt　with　a　loading　of　x　wt%　(xPt(1)/meso-Fe2O3,　x　=　0.08,　0.15,　and　0.25)　catalysts　were　synthesized　via　a　polyvinyl　alcohol-protected　reduction　route.　The　0.25　Pt-1/meso-Fe2O3　sample　showed　much　better　catalytic　activity　than　the　meso-Fe2O3-supported　Pt　nanoparticle　(0.25　Pt-NP/meso-Fe2O3)　sample　for　benzene　combustion,　with　the　temperatures　T-10%,　T-50%,　and　T-90%　(corresponding　to　benzene　conversions　of　10,　50,　and　90%)　were　164,　186,　and　198　degrees　C　at　a　space　velocity　of　20,000　mL/(g　h),　respectively.　The　TOFPt　(2.69　s(_1))　obtained　over　0.25　Pt-1/meso-Fe2O3　at　160　degrees　C　was　much　higher　than　that　(1.16　s(_1))　obtained　over　the　0.25　Pt-NP/meso-Fe2O3　sample　at　160　degrees　C.　Furthermore,　the　0.25　Pt-1/meso-Fe2O3　and　0.15　Pt-1/meso-Fe2O3　samples　exhibited　better　water-resistant　ability　than　the　0.25　Pt-NP/meso-Fe2O3　sample,　which　was　possibly　due　to　formation　of　the　active　radicals　and　decomposition　of　carbonates　in　the　presence　of　moisture.　In　situ　DRIFTS　results　demonstrate　that　the　phenolate　and　benzoquinone　as　well　as　cyclohexanone　and　maleate　were　the　main　intermediates　in　the　oxidation　of　benzene.　The　good　stability　of　the　0.15　Pt-1/meso-Fe2O3　and　0.25　Pt-1/meso-Fe2O3　samples　was　associated　with　the　strong　interaction　between　Pt　and　meso-Fe2O3.