This　paper　presents　a　multi-objective　optimization　strategy　for　the　custom-fit　bra　design　based　on　meta-heuristic　method　of　Genetic　Algorithms　(GA)　for　a　three-dimensional　viscoelastic　breast　model　and　elastic　bra　model.　First,　a　multi-objective　optimization　formulation　with　assigned　weight　factor,　each　objective　function　and　bra　design　variables　including　dimensions　and　material　properties.　For　individual　breast　of　specific　volume　and　material　properties,　the　GA　can　be　customized　to　generate　solutions　for　the　multi-objective　optimization　by　using　predetermined　fit　functions　and　the　methods　to　promote　the　solution　diversity.　Then,　based　on　the　solution　given　from　the　GA,　a　new　Finite　Element　(FE)　simulation　will　be　performed　to　develop　the　three-dimensional　viscoelastic　breasts　and　elastic　bra　models.　The　simulation　results　in　terms　of　contact　pressure,　contact　area,　deformation,　stress　distribution,　and　frictional　force　will　be　used　to　quantitatively　determine　the　optimal　bra　support　with　minimum　pressure.　Finally,　by　integrating　FE　simulation　and　GA,　reasonable　solutions　to　a　multi-objective　design　of　the　custom-fit　bra　can　be　obtained.　Each　solution　satisfies　the　objectives　at　an　acceptable　level　without　being　dominated　by　any　other　solution.　©　2015,　Acta　Press.　All　rights　reserved.