The　aim　of　this　study　is　to　detect　the　carcinogenic　potential　of　three　polycyclic　aromatic　hydrocarbons　(PAHs)　employing　the　novel　cell　model.　The　results　indicated　that　the　novel　cell　model　(an　improved　cell　transformation　assay　using　Balb-E6E7　cells)　could　detect　the　initiating　and　promoting　activities　of　three　PAHs.　The　initiating　and　promoting　activities　of　Benz[a]anthracene　(B[a]A)　were　positive　and　positive　respectively,　whereas　that　of　Benzo[ghi]perylene　(B[ghi]P)　were　negative　and　positive,　respectively.　Pyr　didn’t　show　any　carcinogenic　potential.　The　Balb-E6E7　cell　transformation　assay　possessed　increases　in　transformed　foci　as　many　as　1-10　times　and　one-third　reduction　of　time　consumed　comparing　with　conventional　Balb/c　3T3　cell　system.　According　to　the　standard　of　agents　classified　by　the　IARC,　the　data　demonstrated　the　sensitivity　and　effectiveness　of　the　Balb-E6E7　cell　transformation　assay　were　confirmed　in　predicting　performance　of　PAHs　carcinogenicity　with　the　more　focus　transformation,　less　time　consumed　and　better　performance　of　cost　and　labor.　The　results　might　be　of　significance　for　improving　the　overall　process　of　safety　and　risk　assessment　of　chemical　carcinogens　and　contributing　to　the　cancer　prevention.　©　2015　Taylor　&　Francis　Group,　London.