The　two-point　non-uniformity　correction　based　on　Least　mean　square　(LMS)　algorithm　which　was　proposed　by　Suxia　Xing　need　one　FPGA　processor,　one　DSP　processor　and　four　SRAM　chips.　This　will　increase　the　cost　and　volume　of　the　whole　infrared　system.　In　the　LMS　algorithm,　this　paper　improves　the　estimation　of　the　ideal　signal,　so　that　it　can　reduce　the　influence　of　blind　elements　and　improve　the　effect　of　non-uniformity　correction.　Besides,　this　paper　realizes　the　two-point　non-uniformity　correction　based　on　LMS　algorithm　with　only　one　FPGA　processor　and　two　SRAM　chips　in　the　final,　this　will　reduce　the　volume,　weight,　cost　of　the　whole　infrared　system.　Comparing　with　the　two-point　non-uniformity　correction　based　on　one　FPGA　processor,　this　paper　did　not　need　blackbody　with　uniform　radiation　in　system.　Above　all,　the　method　of　this　paper　is　useful　and　practical.　©　(2014)　Trans　Tech　Publications,　Switzerland.