In　order　to　overcome　the　lack　of　adaptability　and　learning　ability　of　traditional　negotiation,　we　regard　supply　chain　production-marketing　collaborative　planning　negotiation　as　the　research　object,　design　one　five-elements　negotiation　model,　adopt　a　negotiation　strategy　based　on　Q-reinforcement　learning,　and　optimize　the　negotiation　strategy　by　the　RBF　neural　network　and　predict　the　information　of　opponent　for　adjusting　the　concession　extent.　At　last,　we　give　a　sample　that　verifies　the　negotiation　strategy　can　enhance　the　ability　of　the　negotiation　Agents,　reduce　the　negotiation　times,　and　improve　the　efficiency　of　resolving　the　conflicts　of　production-marketing　collaborative　planning,　comparing　to　the　un-optimized　Q-reinforcement　learning.　Copyright　©　2014　SCITEPRESS.