In　the　near-infrared　tomography　of　medical　imaging　technology,　the　accuracy　of　geometric　parameters　about　organism　contour　determines　directly　the　detection　reliability　of　heterogeneity　in　organism　[1,　2].Therefore,　this　paper　takes　the　irregular　convex　body　as　research　object　to　simulate　the　organism　structure　and　uses　the　technology　of　computer　vision　to　acquire　the　3D　point　cloud　in　different　viewing　direction.　Registrating　all　the　views,　the　complete　3D　model　can　be　produced　in　the　end,　which　laid　the　foundation　for　further　study　of　the　near-infrared　diffuse　optical　tomography　technology.　In　this　paper,　we　discuss　the　method　of　3D　registration　based　on　point　laser　markers,　which　has　been　verified　in　experiment.　Experiment　results　showed　that　this　method　can　reproduce　precisely　target　object　and　improve　the　accuracy　of　the　3D　scanning　system.　Besides,　compared　with　the　traditional　marker　method,　this　method　can　recognize　the　marker　easily　and　avoid　the　error　caused　by　pasting　the　markers　on　the　surface　of　target　object.　©　2013　TCCT,　CAA.