Low-dimensional　nanomaterials,　such　as　one-dimensional　(1D)　nanomaterials　and　layered　2D　materials,　have　exhibited　significance　for　their　respective　unique　electronic　and　optoelectronic　properties.　Here　we　show　that　a　mixed-dimensional　heterostructure　with　building　blocks　from　multiple　dimensions　will　present　a　synergistic　effect　on　photodetection.　A　carbon　nanotube　(CNT)-WSe2-graphene　photodetector　is　representative　on　this　issue.　Its　spatial　resolution　can　be　electrically　switched　between　high-resolution　mode　(HRM)　and　low-resolution　mode　(LRM)　revealed　by　scanning　photocurrent　microscopy　(SPCM).　The　reconfigurable　spatial　resolution　can　be　attributed　to　the　asymmetric　geometry　and　the　gate-tunable　Fermi　levels　of　these　low-dimensional　materials.　Significantly,　an　interference　fringe　with　334　nm　in　period　was　successfully　discriminated　by　the　device　working　at　HRM,　confirming　the　efficient　electrical　control.　Electrical　control　of　spatial　resolution　in　CNT-WSe2-graphene　devices　reveals　the　potential　of　the　mixed-dimensional　architectures　in　future　nanoelectronics　and　nano-optoelectronics.