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作者:

Liu, Zhaomiao (Liu, Zhaomiao.) (学者:刘赵淼) | Gao, Lidan (Gao, Lidan.) | Shi, Yi (Shi, Yi.)

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EI Scopus

摘要:

The restenosis after coronary artery bypass graft (CABG) is attributed to the formation of intimal hyperplasia (IH) at the anastomosis, which is closely related to hemodynamic depend on the geometric model. In order to give a reasonable assessment of the surgery effect and judge the longterm patency rate, the hemodynamic of CABG surgery program is compared with that of surgery design of the junction angle changed. Based on in-vivo CT coronary angiography datasets, the individual geometric model of CABG reconstructed instead of idealized geometric models are applied to simulate the real physiological blood flow utilizing pulsatile flow boundary waveforms in the present study. The simulation results show the maximum wall shear rate (WSS) value is at the bottom of anastomosis. Moreover the stagnation zone growing gradually with the greater angle downstream the anastomosis is prone to form the IH, which is consistent with clinical observation. It is proved that the surgery being better suited to maintain graft patency is successful. © 2013 Springer-Verlag.

关键词:

Biomedical engineering Geometry Hemodynamics Medical Physics Physiological models Surgery

作者机构:

  • [ 1 ] [Liu, Zhaomiao]College of Mechanical Engineering and Applied Electronics Technology, Beijing University of Technology, Pingleyuan 100, Beijing, China
  • [ 2 ] [Gao, Lidan]College of Mechanical Engineering and Applied Electronics Technology, Beijing University of Technology, Pingleyuan 100, Beijing, China
  • [ 3 ] [Shi, Yi]Department of Cardiac Surgery, FuWai Hospital, Chinese Academy of Medical Sciences, Beijing, China

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ISSN: 1680-0737

年份: 2013

卷: 39 IFMBE

页码: 184-187

语种: 英文

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