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The prefrontal cortex is crucial for memory encoding and processing, in which the lateral prefrontal cortex (LPFC) is more involved in semantic and episodic memory, whereas the medial prefrontal cortex (MPFC) is more related to the associative information processing and social cognition. Social statistical information is a kind of typical associative information with sociality. However, the role of the prefrontal cortex in comprehending the social statistical information remains unknown yet. This study focused on the brain activities of 36 normal subjects in the prefrontal cortex using fMRI while they viewed the social statistical information presented in either visual form as a graph or textual form as a verbal description of the information in the graph. The results showed that the graph and textual tasks consistently activated the anterior and posterior portions of ventrolateral prefrontal cortex (VLPFC), the dorsal and ventral MPFC. The results suggest that the VLPFC and the MPFC commonly contribute to the social statistical information processing. © Springer International Publishing 2013.
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