In　this　paper,　the　system　configuration　and　design　scheme　of　a　data　acquisition　system　based　on　a　time　delay　integration　and　charge-coupled　device　(TDI　CCD)　are　introduced.　The　circuit　design　principle　and　implementation　of　TDI　CCD　driving　pulses　are　presented,　which　are　confirmed　by　Quartus　II　simulation　with　the　Verilog　Hardware　Description　Language　(Verilog　HDL).　The　output　signals　of　TDI　CCD　are　first　conditioned　with　the　technique　of　correlated　double　sampling　(CDS),　then　converted　with　an　analog-to-digital　(A/D)　chip,　and　finally　transferred　to　computer　though　a　USB　interface.　The　system　can　be　used　in　human　body　imaging,　such　as　head,　teeth　and　palm　and　so　on.　©　2012　IEEE.