Nowadays,　modern　manufacturing　enterprises　not　only　need　to　ensure　the　variety　of　products,　but　also　need　to　strive　for　the　lowest　cost　and　the　ability　to　quick　respond　to　uncertain　market.　Hence,　the　enterprises　prefer　to　lean　supply　chain,　agile　supply　chain　and　leagile　(Lean　and　agile,　leagile)　supply　chain.　These　kinds　of　supply　chains　have　some　uncertainties　of　the　supply,　production,　assembly,　sales　and　other　aspects,　and　they　are　complex,　nonlinear　and　dynamics　systems.　This　paper　first　adopted　the　leagile　supply　chain,　and　compared　the　main　characteristics　of　lean　supply　chain,　agile　supply　chain　and　leagile　supply　chain.　And　then,　this　paper　summarized　the　detailed　main　characteristics　of　leagile　supply　chain,　and　these　main　characteristics　can　improve　the　efficiency　of　supply　chain,　and　weaken　the　＇bullwhip　effect＇　effectively.　At　last,　according　to　the　need　of　manufacturing　enterprises,　this　paper　based　on　the　main　characteristics　gave　application　of　leagile　supply　chain　in　manufacturing　industry.　This　paper　will　lay　a　theoretical　foundation　for　the　further　research　on　supply　chain.　©　2011　IEEE.