Cardiopulmonary　auscultation　is　one　of　basic　curriculum　of　medical　students.　Generally,　the　multimedia　is　used　to　group　teach　auscultation　techniques　via　classroom　demonstration.　However,　due　to　the　lack　of　authenticity　and　interactivity　features,　this　approach　is　not　fundamentally　to　meet　the　modern　teaching　of　medical　simulation　teaching　situations　and　individual　teaching　needs.　The　advancement　of　electronic　and　digital　signal　processing　technologies　facilitates　simulating　this　learning　environment.　This　study　aims　to　develop　a　cardiopulmonary　auscultation　simulation　teaching　system　for　assisting　teachers　and　nursing　students　in　auscultation　teaching　and　learning.　Cardiopulmonary　auscultation　simulation　teaching　system　includes　a　simulation　patient,　a　simulation　electronic　stethoscope,　a　remote　control,　a　receiver　on　PC　and　the　software　package.　The　simulation　stethoscope　provides　the　user　with　the　sounds　of　12　heart　pathological　features　and　16　lungs　pathological,　when　move　the　simulation　stethoscope　to　the　corresponding　region　on　the　simulation　patient　after　choosing　the　diseases　by　the　remote　control.　At　the　same　time,　the　receiver　on　PC　could　receive　the　data　sent　from　the　simulation　stethoscope.　In　addition,　the　software　can　display　the　current　disease,　disease　characteristics　profiles,　the　current　location　of　the　stethoscope　and　the　stethoscope　auscultation　sound　wave,　etc.　©　2011　IEEE.