Using　a　novel　wide-view　visual　presentation　system　for　vision　research　developed　by　us　and　visual　retinotopic　mapping　functional　magnetic　resonance　imaging　(fMRI).　We　have　investigated　the　variation　of　BLOD　response,　in　three　visual　areas　(V1-V3),　as　a　function　of　visual　retintotopic　areas　and　five　contrast　levels　(96%,　48%,　24%,　12%　and　6%).　Each　visual　area　was　identified　in　each　subject　using　a　combination　of　retinotopic　mapping　methods　and　cortical　flattening　techniques.　A　checkerboard　patterns　with　five　level　contrasts　were　used　as　the　stimuli　in　this　study.　We　also　constructed　BLOD　responses　amplitude　tuning　curves,　averaged　across　subjects,　for　three　visual　areas　(V1-V3)　and　three　eccentricities　(0-20°,　20-40°,　40-60°).　The　result　indicated　that　the　peripheral　stimulation　would　lead　to　lower　BLOD　responses,　compared　with　the　visual　areas　relative　to　central　field　stimulation.　The　present　signal　change　of　each　visual　area　is　consistent　with　the　known　physiological　properties　of　cells　in　the　corresponding　macaque　visual　areas　in　previous　functional　imaging　studies.　In　presented　study,　we　confirmed　visual　areas　V3　showed　more　sensitivity　to　contrast,　than　V2,　and　than　V1　in　central　and　peri-central　visual　area.　More　importantly,　we　revealed　the　biological　responses　for　peripheral　visual　areas　(40-60°),　which　the　V1-V3　had　BLOD　signal　change　only　for　higher　contrast　(96%and　48%),　but　no　BLOD　response　for　lower　contrast　(24%,　12%　and　6%).　©2010　IEEE.