People　have　paid　close　attention　to　melamine　by　Sanlu　Event.　Melamine,　a　widely　used　as　an　organic　chemical　in　industry,　was　added　in　milk　to　increase　the　protein　content.　Obviously,　traditional　kjeldahl　hasn＇t　suitable　to　detect　real　protein　content.　Focusing　on　the　milk　with　melamine　in　market,　a　rapid　and　easy　method　is　necessary　to　meet　the　needs　to　detect　melamine　from　the　milk.　In　this　study,　the　analytical　system　was　developed　by　surface　enhanced　Raman　spectrum　(SERS)　and　portable　Raman　spectrometer,　which　had　fast　detecting　and　alarming　functions.　Firstly,　Qualitative　analysis　method　for　detecting　melamine　in　milk　was　found.　And　the　peak　709cm-1　was　used　as　the　essential　peak　for　qualitative　analysis　method.　On　the　basis　of　that,　quantitative　method　was　further　defined.　The　concentration　of　melamine　in　milk　vs　Ratio　of　709cm-1/1026cm-1　showed　a　good　linear　relationship　when　the　standard　concentration　of　melamine　in　milk　within　3ppm　to　10ppm.　Detective　limit　of　this　method　was　1ppm,　and　the　quantization　limit　was　3ppm.　Recovery　was　in　86%　to　106%　and　satisfied　the　request　of　GB/T22388-2008　(80%-110%).　Analytical　system　was　established　for　determination　melamine　in　milk.　Multiple　functions　were　contained　in　this　system.　Detecting　and　result　were　completed　rapidly　by　used　analytical　system　on　condition　that　the　concentration　of　melamine　within　3ppm　to　10ppm.　The　red　signal　was　displaying　at　concentration　above　3ppm,　and　the　green　signal　was　giving　at　concentration　below　3ppm.　In　a　word,　the　application　of　this　analytical　system　has　an　important　significance　in　false　protein　identification,　milk　safety　control　and　people　health　protection.　©2009　IEEE.