CD138　immune　magnetic　beads,　made　from　CD138　antibody　and　nano-gold　magnetic　beads,　can　be　used　to　separate　multiple　myeloma(MM)cells　from　others.　The　enriched　MM　cells　are　used　for　chromosome　examination　by　the　way　of　FISH　(Fluorescence　in　situ　hybridization),　which　is　important　for　disease　prognosis.　Now　in　domestic　it　must　be　imported,　and　has　a　high　price.　We　ourselves　make　CD138　immune　magnetic　beads,　and　evaluate　sorting　efficiency　using　RPMI-8226　myeloma　cell　line.　©2009　IEEE.