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Based on a new way to compute check points, this paper presents a 'Block Recursive' sequence alignment algorithm, which can run in a time requirement between 1.5mn and 3mn in general cases but between 1.5mn and 2mn for sequences with high similarities. Still, the algorithm keeps a linear space requirement and always guarantees an optimal alignment result. Some experiments show that it runs at least 10% faster than the Hirschberg algorithm if the two compared sequences has a normalized edit distance less than 0.25. © 2008 IEEE.
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