Femoral　bypassing　remains　an　effective　surgical　technique　to　rescue　lower　extremity　peripheral　vascular　diseases.　A　great　number　of　grafts　have　moderate　patency　rates　and　will　fail　in　the　long　term.　Geometry　configuration　is　considered　to　have　direct　influences　on　the　hemodynamics　which　is　correlated　with　the　pathological　changes　of　bypassed　femoral　arteries.　The　overall　goal　of　the　present　study　is　to　investigate　the　hemodynamic　influences　of　a　new　anastomosis　configuration　on　the　pathological　mechanisms　of　intimal　hyperplasia　and　restenosis　that　result　in　the　bypassing　surgery　failure.　The　authors　presented　a　novel　anastomosis　configuration　with　symmetric　2-way　bypass　grafts　for　the　purpose　of　improving　the　hemodynamics.　The　physiological　blood　flows　in　the　conventional　1-way　model　and　the　presented　2-way　model　of　fully　stenosed　femoral　bypass　grafts　were　simulated　with　computational　approaches.　The　temporal　and　spatial　distributions　of　flow　patterns　and　wall　shear　stresses　in　the　vicinity　of　distal　anastomosis　were　analyzed　and　compared.　The　result　of　the　present　study　indicates　that　the　2-way　model　is　featured　with　larger　longitudinal　velocity,　less　refluence　and　eddy　flow,　more　uniform　wall　shear　stress　distribution　and　smaller　magnitude　of　wall　shear　stress　gradient.　All　of　these　features　demonstrate　that　the　hemodynamics　in　the　symmetric　2-way　bypass　graft　is　significantly　improved　and　is　quite　favorable　for　alleviating　the　intimal　hyperplasia　and　restenosis　and　ameliorating　the　patency　rates　of　femoral　bypass　graft.　One　of　the　possibilities　which　the　present　study　can　offer　is　enabling　the　surgeon　to　gain　an　approximate　idea　of　the　hemodynamic　conditions　that　will　occur　after　the　implantation　of　a　symmetric　2-way　bypass　graft　and　to　control　over　the　geometry　configuration　of　the　anastomosis　in　order　to　achieve　optimal　hemodynamics　and　to　maximize　the　success　rates　of　bypassing　surgery.