This　paper,　combining　the　theories　of　ecology　and　the　regional　technological　innovation　system　(RTIS),　first　advances　a　new　concept:　the　regional　technological　innovation　ecosystem　(RTIE),　which　consists　of　the　composite　organizations　and　the　organizations　with　a　composite　environment　for　regional　technological　innovation.　RTIS　with　characteristics　and　regularities　of　the　ecosystem　has　provided　us　with　a　new　thought　for　the　study　of　RTIE.　The　discussion　will　only　focus　on　the　restrictive　factors　of　various　kinds　in　RTIE,　i.e.　the　technological　factors,　the　market　factors,　ecological　environment　factors　as　well　as　system　and　policy　factors,　and　how　composite　organizations　cope　with　the　changes　of　restrictive　factors　in　the　system　along　with　the　strategies　that　they　should　take　for　adaptation　to　these　changes.