In　a　real　network　environment,　multiple　types　of　attacks　can　occur.　The　more　important　the　service　or　network,　the　more　attacks　it　may　suffer　simultaneously.　Moving　target　defense　(MTD)　technology　is　a　revolutionary　game-changing　cyberspace　technology　that　has　found　various　applications　in　recent　years.　However,　the　existing　strategies　are　targeted　at　defending　against　specific　types　of　attacks　and　do　not　meet　the　security　requirements　for　multiple　attacks.　Therefore,　we　propose　a　joint　defense　strategy　based　on　the　MTD　that　can　select　one　or　multiple　mutant　elements　to　defend　against　different　types　of　attacks.　In　addition,　we　use　the　analytic　hierarchy　process　(AHP)　to　quantify　the　factors　affecting　the　attack　and　defense　costs.　After　comprehensively　analyzing　the　effects　of　the　different　MTD　technologies　against　different　attacks,　we　propose　an　efficient　strategy　selection　algorithm　based　on　joint　defense.　Finally,　we　conduct　experiments　to　evaluate　the　selection　of　a　joint　defense　strategy　under　multiple　attacks.　The　experimental　results　demonstrate　the　feasibility　and　effectiveness　of　the　proposed　joint　defense　strategy　selection　approach.