A　high-speed　railway　station　with　large　space　serves　a　big　flow　of　people.　If　there　is　no　clear　guidance,　it　is　easy　to　get　lost,　leading　to　the　interruption　of　the　passenger＇s　route.　To　solve　these　problems,　this　paper　relied　on　Beijing　South　Railway　Station　to　study　guiding　signs　settings　in　the　entrance　space　of　high-speed　railway　stations.　First,　the　universality　and　characteristics　of　interruption　were　summarized　by　tracking　observation.　Second,　the　underlying　causes　of　interruption　by　interview　method　were　analyzed.　Finally,　based　on　the　result　of　the　problem　analysis,　the　strategies　were　put　forward　for　location　and　information　setting　of　the　guiding　signs.　Results　show　that　the　interruption　of　flow　is　widespread　and　concentrated　mainly　in　waiting　area　and　ticket　area.　The　guiding　signs　is　an　important　cause　of　interruption.　The　problems　focus　on　the　location　and　information　settings　of　the　guiding　signs.　The　research　results　can　be　used　as　the　theoretical　basis　for　the　guiding　signs　settings　in　the　entrance　space　of　the　high-speed　railway　station.　©　2019,　Editorial　Department　of　Journal　of　Beijing　University　of　Technology.　All　right　reserved.