With　the　explosive　increase　of　mobile　data　traffic,　content　delivery　issue　on　the　Internet　is　a　growing　concern　for　both　Internet　service　providers　(ISPs)　and　content　providers　(CPs).　To　improve　content　transmission　efficiency　and　reduce　network　delay,　many　ISP-CP　cooperation　schemes　are　designed,　parts　of　which　are　trying　to　introduce　the　idea　of　in-network　caching.　However,　the　combination　influence　of　edge　cache　and　content　popularity　is　largely　ignored　in　the　existing　solutions.　Therefore,　we　propose　a　novel　edge　cache-based　ISP-CP　collaboration　model　for　content　delivery　services,　where　the　two　important　factors　are　simultaneously　taken　into　account.　Then,　the　model　is　analyzed　to　obtain　the　maximal　network　profit　from　the　perspective　of　online　and　offline.　The　simulation　results　show　that　the　profit　gains　of　the　proposed　solution　over　the　existing　Internet　models　only　considering　cooperation　between　ISPs　and　CPs　in　the　heterogeneous　network　environments.