This　article　presents　a　comparative　investigation　on　mechanical　behavior　and　construction　characteristics　of　some　typical　connections　in　cold-formed　thin-walled　steel.　The　lap　shear　tests　of　96　specimens　considering　four　typical　connections　with　a　self-piercing　rivet,　clinching,　self-drilling　screw,　and　blind　rivet　were　conducted.　The　effects　of　sheet　thickness　and　thickness　ratio　on　failure　modes　and　mechanical　behavior　of　the　four　types　of　connections　were　investigated.　Through　analyzing　the　feasibility　of　mechanic　and　construction,　the　applicability　of　the　four　types　of　connections　in　fabricated　cold-formed　steel　structures　was　comprehensively　evaluated.　The　result　of　the　research　shows　that　compared　with　the　other　three　connections,　self-piercing　rivet　connections　are　more　suitable　for　modularly　fabricated　cold-formed　steel　structures　because　of　its　superior　mechanical　properties,　well-formed　quality,　high　efficiency,　and　potential　industrialization.　Based　on　the　design　methods　of　fasteners　in　North　American　(AISI　S100-16)　and　European　standards　(prEN1999-1-4)　on　cold-formed　steel　structures,　an　appropriate　design　method　is　proposed　for　self-piercing　riveting　connections.