Earthquakes　act　as　a　dominant　trigger　for　failure　of　slopes　in　seismic　active　regions.　In　this　study,　a　seismic　stability　analysis　of　a　three-dimensional　(3D)　rock　slope　in　Hoek-Brown　media　is　conducted　based　on　the　limit　analysis　method.　The　energy　balance　equation　is　derived　by　equating　the　external　work　rate　by　rock　mass　weight　and　seismic　forces　to　the　internal　energy　dissipation　rate,　and　an　optimization　code　is　then　programmed　to　capture　the　optimized　factor　of　safety　(FoS)　of　a　3D　rock　slope　based　on　the　strength　reduction　technique.　The　validity　of　the　equivalent　Mohr-Coulomb　parameters　method　and　generalized　tangent　technique　in　conjunction　with　the　limit　analysis　method　to　estimate　FoS　of　a　3D　rock　slope　is　investigated.　Subsequently,　a　quasi-static　method　is　used　to　explore　the　effect　of　seismic　forces　on　stability　of　a　3D　rock　slope.　The　results　of　the　parametric　analysis　indicate　that　the　seismic　force　exhibits　significant　negative　effects　on　the　stability　of　a　3D　slope　and　that　a　significant　difference　exists　between　a　3D　FoS　solution　and　a　solution　obtained　under　two-dimensional　(2D)　plane　strain.　A　stability　chart　analysis　is　performed　to　produce　a　set　of　seismic　stability　charts　for　preliminary　design　purposes.　Finally,　a　case　study　is　performed　to　apply　stability　charts　in　practical　situations.