As　the　Cr2O72-　anion　is　highly　toxic,　new　sensors　have　been　developing　for　its　effective　detection　from　water,　among　which　metal-organic　frameworks　(MOFs)　show　distinct　superiority　over　many　other　materials.　Herein,　a　new　fluorescent　Zr(IV)-based　MOF,　[Zr6O4(OH)(8)(H2O)(4)(sbtc)(2)]　(referred　to　as　BUT-28),　based　on　the　di-isophthalate　ligand　with　a　central　CH=CH　moiety,　trans-stilbene-3,3＇,5,5＇-tetracarboxylate　(sbtc(4-)),　has　been　prepared　and　structurally　determined.　The　MOF　shows　excellent　stability　in　neutral,　highly　acidic,　and　weakly　basic　aqueous　solutions.　Moreover,　no　essential　uptake　loss　in　three　cycles　of　water　vapor　adsorption-desorption　measurements　was　observed　for　BUT-28,　suggesting　the　robustness　of　the　porous　framework　and　its　great　potential　for　long-term　use.　Fluorescent　measurements　were　carried　out　for　BUT-28　and　an　isostructural　MOF,　Zr-abtc,　which　is　constructed　from　the　di-isophthalate　ligand　with　a　central　N=N　moiety,　azobenzene-3,3＇,5,5＇-tetracarboxylate　(abtc(4-)).　Interestingly,　Zr-abtc　shows　very　weak　fluorescent　emission.　In　contrast,　BUT-28　exhibits　relatively　strong　fluorescence　and　serves　as　a　promising　sensory　material　for　the　detection　of　trace　Cr2O72-　(limit　of　detection:　36　ppb)　in　aqueous　solutions　by　selective　and　sensitive　fluorescence　quenching　effect.