Cryptomelane-type　manganese　oxide　octahedral　molecular　sieve　(OMS-2)-supported　Ag　(xAg/OMS-2;　x　=　1.0,　3.0,　5.0,　7.0,　9.0,　and　10.0　wt%)　catalysts　were　prepared　by　a　pre-incorporation　method.　These　materials　were　used　as　catalysts　for　benzene,　toluene,　and　formaldehyde　oxidation　to　investigate　the　effects　of　support　structures　on　the　interaction　between　Ag　and　OMS-2　and　the　catalytic　activity.　The　physicochemical　properties　of　the　samples　were　characterized　by　XRD,　FT-IR,　BET,　TEM,　XPS,　O-2-TPD,　H-2-TPR,　and　NH3-TPD　techniques.　The　results　show　that　the　loaded　Ag　exerted　an　important　influence　on　the　physicochemical　properties　of　the　sample.　The　Ag　particles　were　homogeneously　dispersed　on　the　surface　of　xAg/OMS-2.　The　catalytic　activity　of　OMS-2　was　greatly　improved　after　loading　silver.　The　9　wt%　Ag/OMS-2　sample　showed　the　best　activity　(T-90%　was　362,　270,　and　168　degrees　C　for　benzene,　toluene,　and　formaldehyde　oxidation,　respectively),　which　was　due　to　the　higher　surface　Mn3+/(Mn4+　+　Mn3+)　atomic　ratio,　a　greater　amount　of　active　oxygen　species,　better　low-temperature　reducibility,　and　higher　acidity.　It　is　concluded　that　the　excellent　catalytic　performance　of　9　wt%　Ag/OMS-2　was　associated　with　the　interaction　between　the　Ag　particles　and　the　OMS-2　support.