In　this　study,　enhanced　dark-field　hyperspectral　imaging　(ED-HSI)　was　employed　to　directly　observe　acetaminophen　(AAP),　a　model　pharmaceutical　and　personal　care　product　(PPCP),　adsorbed　on　multiwalled　carbon　nanotubes　with　large　diameters　(L-MWCNT)　and　small　diameters　(S-MWCNT)　under　equilibrium　conditions.　The　ED-HSI　results　revealed　that　(1)　AAP　molecules　primarily　adsorbed　onto　the　external　surfaces,　rather　than　the　internal　surfaces　of　L-　and　S-MWCNT　aggregates,　(2)　or　on　sidewall　of　the　dispersed　tubes,　but　not　at　their　end　caps.　Besides,　ED　HSI　images　showed　that　the　surface　coverage　ratio　of　AAP/S-MWCNT　is　smaller　than　that　of　AAP/L-MWCNT　(1.1　vs　3.4),　indicating　that　there　are　more　available　adsorption　sites　on　S-MWCNT　than　L-MWCNT　when　the　adsorption　reached　equilibrium.　This　finding　was　consistent　with　the　adsorption　capacities　of　S-MWCNT　and　L-MWCNT　(252.7　vs　54.6　mg　g(-1)).　Direct　visualization　of　sorption　sites　for　PPCP　molecules　provides　new　insights　into　the　heterogeneous　structures　and　surface　properties　of　MWCNT　and　helps　elucidate　the　adsorption　mechanisms　that　are　fundamental　to　the　design　of　functional　adsorbents　for　PPCP　contaminants.