In　the　design　and　construction　of　metal-organic　frameworks　(MOFs),　the　utilization　of　slim　ligands　is　usually　more　inclined　to　form　interpenetrated　structures　compared　with　bulky　ones.　The　structural　interpenetration　can　improve　the　framework　stability　and　in　some　cases,　enhance　gas　adsorption　capacity　and　selectivity　due　to　confined　pores.　In　order　to　explore　the　structural　control　of　MOFs　and　construct　new　MOFs　with　good　selective　gas　adsorption　ability,　herein,　a　slim　ethynyl-based　4-connected　carboxylate　acid　ligand,　4,4,4,4-(benzene-1,2,4,5-tetrayltetrakis(ethyne-2,1-diyl))tetrabenzoic　acid　(H4BTEB),　was　used　to　design　and　construct　MOFs,　hopefully　having　interpenetrated　structures.　Combining　with　4-connected　paddle-wheel　Cu-2(COO)(4)　and　8-connected　Zr6O4(OH)(8)(COO)(8)　clusters,　BTEB4-　ligand　led　to　two　new　MOFs,　[Cu-2(BTEB)(H2O)(2)]　(BUT-43)　and　[Zr6O4(OH)(8)(H2O)(4)(BTEB)(2)]　(BUT-44).　As　expected,　the　two　MOFs　have　two-fold　interpenetrated　framework　structures　with　partitioned　channels.　BUT-43　contains　a　rare　three-dimensional　(3D)　4-connected　single　network　with　lvt　topology,　which　then　interpenetrates.　In　BUT-44,　each　Zr-6-based　cluster　is　coordinated　with　eight　BTEB4-　ligands　to　give　a　single　3D　4,8-connected　scu　network,　which　then　doubly　interpenetrates　to　give　the　first　example　of　interpenetrated　4,8-connected　Zr(iv)-MOF.　Studies　on　their　stability　and　gas　adsorption　properties　demonstrate　that　BUT-44　shows　higher　stability　in　NaOH　solution　of　pH　10　and　1　M　HCl　aqueous　solution.　More　interestingly,　both　MOFs　represent　good　gas　adsorption　selectivities　for　C2H2　over　CO2　and　CH4,　suggesting　potential　application　in　gas　separation.