Reinforced　concrete　(RC)　flat　slab　column　structure　is　a　typical　vertical　support　system　and　is　often　used　in　regions　of　moderate　seismicity.　Additionally,　a　steel　structure　is　easy　to　assemble　and　exhibits　good　mechanical　property,　ductility　and　energy　dissipation　performance.　Thus,　this　study　presents　a　new　type　of　connection　between　a　prefabricated　RC　flat　slab　and　square　steel　tube　column.　The　connection　effectively　improves　seismic　performance　and　stress　mechanism　and　leads　to　plastic　deformation　in　the　cantilever　beams　that　can　be　replaced　after　an　earthquake.　The　connection　consists　of　a　column　base　with　four　cantilever　beams,　a　channel　steel　connection,　and　an　RC　flat　slab.　A　gap　connected　by　four　square　crossing　I-steel　cantilever　beams　is　left　between　the　column　and　channel　steel　connection,　and　this　forms　an　opening　around　the　column.　An　experiment　was　performed　to　study　the　seismic　behaviour　of　the　prefabricated　slab　column　connection.　The　effects　of　the　key　parameters　including　the　I-steel　web　thickness　of　the　cantilever　beam　and　axial　compression　ratio　were　investigated.　The　failure　modes,　hysteretic　curves,　and　stress-strain　curves　with　respect　to　relevant　components　were　presented.　A　numerical　simulation　verified　by　the　tests　was　performed　to　analyse　the　section　stress　and　bolt　forces　for　making　up　the　test　deficiency.　The　results　indicated　that　the　prefabricated　slab　column　connection　exhibits　a　superior　seismic　performance,　thereby　leading　to　earthquake-resilience.　Finally,　design　considerations　were　presented　to　guide　engineering　practice　for　the　proposed　prefabricated　slab　column　connection.