Water　adsorption　of　metal-organic　frameworks　(MOFs)　is　attracting　intense　interest　because　of　their　potential　applications　in　atmospheric　water　harvesting,　dehumidification,　and　adsorption-based　heating　and　cooling.　In　this　work,　through　using　a　hexacarboxylate　ligand,　four　new　isostructural　Zr(IV)-MOFs　(BUT-46F,　-46A,　-46W,　and　-46B)　with　rare　low-symmetric　9-connected　Zr-6　clusters　were　synthesized　and　structurally　characterized.　These　MOFs　are　highly　stable　in　water,　HCl　aqueous　solution　(pH　=　1),　and　NaOH　aqueous　solution　(pH　=　10)　at　room　temperature,　as　well　as　in　boiling　water.　Interestingly,　the　rational　modification　of　the　metal　clusters　in　these　MOFs　with　different　functional　groups　(HCOO-,　CH3COO-,　H2O/OH,　and　PhCOO-)　enables　the　precise　tuning　of　their　water　adsorption　properties,　which　is　quite　important　for　given　application.　Furthermore,　all　four　MOFs　show　excellent　regenerability　under　mild　conditions　and　good　cyclic　performance　in　water　adsorption.